1- EXOSOME HAIR TRANSPLANT

Exosomes are small bubbles that enable communication between cells and help rejuvenation as an important biological agent used in treatments such as hair transplantation and skin rejuvenation. They are usually released from stem cells and contribute to the transfer of information and signals between cells.Exosome hair transplant is used to support the healing processes of tissues and organs affected by causes such as ageing, chronic diseases, environmental factors and genetic disorders. This hair transplant is effective in regulating regenerative processes in target tissues, as exosomes contain intracellular information and proteins. Furthermore, exosomes can help calm and regulate an over-reactive immune system by transferring from NK cells to T-Regulatory cells.

Exosomes, unlike stem cells, offer a treatment option that does not require surgical procedures and may carry a lower risk of complications. Furthermore, unlike the use of embryonic stem cells, exosomes do not pose a risk of tumour development and are obtained safely. Exosome hair transplant can be used in many indications such as skin rejuvenation, spot treatments, acne scar treatments, porous skin tightening, hair loss and atopic dermatitis. Exosomes can increase fibroblast cell proliferation, promote collagen and elastin synthesis and promote skin rejuvenation processes through the proteins and miRNAs they contain.

Therefore, exosomes are an important area of research used in modern regenerative medicine and are becoming increasingly important among treatment options. However, it is important that treatment protocols are correctly implemented and managed by specialists.

EXOSOME IN HAIR TRANSPLANTATION

The use of exosomes is very important for the survival, nutrition and strengthening of grafts taken from the living environment. It is important to keep these grafts in a place with a living environment for their nutrition and continuation of their vitality. The grafts are kept in a solution containing the exosome, which consists of factors in the stem cells, for the continuation and strengthening of its vitality. Exosome ensures that the graft remains alive, continues to be nourished and strengthened. In this way, a perfect hair transplantation model is formed. Thus, the grafts are alive, nourished and strengthened when they are taken from the scalp, which is a weakened feeding point and taken into a very high-rich exosome environment.

Exosomes are small bubbles used in treatments such as hair transplantation and help rejuvenation by providing communication between cells. Usually released from stem cells, exosomes contain intracellular information and proteins that are effective in regulating regenerative processes in target tissues. Exosome hair transplant is used to support the healing processes of tissues and organs affected by aging, chronic diseases, environmental factors and genetic disorders. This treatment provides positive effects such as increasing fibroblast cell proliferation, supporting collagen and elastin synthesis and promoting skin rejuvenation processes thanks to exosomes.

Exosome hair transplant can be successfully used in different indications such as skin rejuvenation, spot treatments, acne scar treatments, porous skin tightening, hair loss and atopic dermatitis. Vitality and natural hair transplantation are achieved by using solutions enriched with exosomes to keep the grafts alive, nourished and strengthened. Therefore, exosomes are considered an important area of research in modern regenerative medicine and are becoming increasingly important among treatment options. In order to use exosomes effectively, it is of great importance that the correct treatment protocols are applied and managed by experts.

Advantages

• -Exosomes, unlike stem cells, do not require a surgical procedure.
• -Exosomes can last longer because they are protein-containing. Thus, it ensures that the main structure of the grafts is safely stored and protected during the hair transplantation operation.
• -It has a lower risk of complications.
• -Perfect hair transplantation results are obtained by revitalising, nourishing and strengthening the grafts.
• -Exosomes, unlike embryonic stem cells, do not pose a risk of tumour development.
• -They are obtained safely.
• -It promotes the rejuvenation processes of the skin.
• -Exosomes can be freeze-dried, packaged and transported.

How to Obtain Exosome?

Cells obtained from the umbilical cord tissue of a newborn are cultured in special culture containers with cell-specific medium to propagate them. After the cells are multiplied, dead cell residues are removed from the culture environment. Following the pre-processing steps, exosomes are isolated using ultracentrifugation, which involves high-speed spinning. Once the obtained exosomes pass quality control tests, they are packaged into product vials and stored under appropriate conditions. MSC Exosomes Effect on Hair Loss

• -Increases the number of hair follicles in the growth phase.
• -Dermal papilla cells that form hair follicles regenerates.
• -In the early stages of hair loss, exosome by applying growth factors with the application of hair regrowth in men and womenand can be regenerated.
• -After the first application of Exosome hair transplant A noticeable change within 1 or 2 months can be seen, but the most significant changes are between 6 It is observed between 12th months.
• -Exosomelar hair growth prolongs the hair cycle and followed by the resting phase (telogen phase) hair follicles into the growth phase (anagen phase) by transforming it.